Bulletin of ANPA

Abstract submitted to ANPA Conference July 14–16, 2023

Volume 5, Number 1

Biological, Medical, Soft Matter and Chemical Physics

Abstract ID: ANPA2023-N00041

Abstract:

ANPA2023-N00041: Vibrational spectra of DNA and RNA Segments

Authors:

• Saniya L. Lyles; Department of Chemistry, Physics and Materials Science, Fayetteville State University, Fayetteville, North Carolina 28301, United States

• Chandra M. Adhikari, Bhoj R. Gautam; Department of Chemistry, Physics and Materials Science, Fayetteville State University, Fayetteville, North Carolina 28301, United States

Biological macromolecules Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA) store and transmit genetic information from generation to generation. DNA and RNA are essential nucleic acids of all living organisms having the capacity to self-replicate. In the literature, various models are used to study DNA and RNA molecules. In this study, we model a DNA molecule as the four nitrogenous bases, namely adenine (A), cytosine (C), guanine (G), and thymine (T), connected by linear springs that vary in stiffness. The same for RNA molecules are the four nitrogenous bases, adenine (A), cytosine (C), guanine (G), and uracil (U), connected by linear springs with varying stiffness. Shorter pieces of modeled DNA and RNA structure have more "singularities," which create more bands in their density of states (DOS) plot, like those of infinite systems. As the length of these macromolecules and the number of parts increases, the impact of randomness on the way they move decreases, making the DOS plots more symmetrical. This work is supported by the National Science Foundation RIA 1900998.

To cite this abstract, use the following reference: https://anpaglobal.org/conference/2023/ANPA2023-N00041